About me


Adams face

Adam Cribbs: PhD (Imperial college, London) in molecular immunology and now a computational biologist.



My passion is for quality reproducible science that has the power to change opinions about the world.



I am currently working as a Medical Research Council (MRC) fellow at the Computational Genomics and Training Centre (CGAT), University of Oxford.


Im also an immunologist with a focus on understanding how dysregulated epigenetic pathways in T cells contribute to autoimmunity.


I am currently applying my bioinformatic skills to answer important research questions in collaboration with a number of academics across the University of Oxford. Summaries of current ongoing projects are detailed here.

My Philosophy


A historical perspective


I began my scientific career at the Kennedy Institute of Rheumatology where I undertook a PhD investigating why regulatory T cells (Treg) were defective in Rheumatoid arthritis (RA). I identified that DNA methylation at the CTLA-4 promoter led to impaired Treg function that contributes to the inflammatory processes in RA

Following my PhD I moved to Prof Sir Marc Feldmann (known for the discovery of anti-TNF therapy in RA) and Prof Udo Oppermans laboratory at the Botnar research centre to investigate epigenetic pathways that are important for T and NK cell activation. During this time I was using a number of whole genome wide techniques to analyse the contribution of histone marks to autoimmunity

Despite developing extensive knowledge of experimental design and state-of-the art laboratory techniques, at the time I was unable to analyse the resulting data to a high standard, which motivated me to apply for my current MRC fellowship in computational biology based at the Weatherall Institute of Molecular Medicine (University of Oxford).

The CGAT training fellowship is a highly competitive program that has the remit of “training the future leaders in computational genomics”. Since starting the program, I have developed a number of computational skills that allow me to write complex code, enabling the difficult analysis and interpretation of next-generation sequencing data.

I am currently working on a number of really cool projects in collaboration with a number of scientists across the University of Oxford, summaries of these can be found here.

Kennedy institute
The Kennedy Institute of Rheumatology
Botnar Research Centre
The Botnar Research Centre
WIMM
The Weatherall Institute of Molecular Medicine


10 random things


  • Over a thousand evangelical christians have prayed for me. (I'm not religious)
  • I don't have a favourite food - I love all food, how could I choose!
  • I'm from the north east of England, a town called Whitley Bay.
  • I'm a member of Campion hall, a Jesuit priest order in Oxford (I'm not a priest).
  • If I wasn't a scientist I would be an engineer or a software developer.
  • I recently broke my hand after a fat man sat on it.
  • I have a secret....I used to be a stamp collector.
  • Coding is my new hobby and I hope to get good at it...one day :).
  • I used to be a competitive swimmer.
  • I object to queueing, filling in unnecessary paperwork and to overly organised people.
  • I love walking, talking and musicing.